FAM189B

Across TCGA patient cohorts, FAM189B protein abundance is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM189B-associated genes across cancer lineages are CGB2, MVB12A, and ZNF37CP. Each is linked with FAM189B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM189B-to-partner and partner-to-FAM189B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189B versus CGB2 in HNSC, with a Pearson correlation of 0.96.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189B→partner) and Y-score (partner→FAM189B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CGB2 →	+0.180	+0.287	.003	.002	2	1
HNSC	MVB12A →	+0.524	+0.303	<.001	.006	2	1
HNSC	ZNF37CP →	+1.280	+0.287	.001	.002	2	1
HNSC	PPP1R3A →	+1.180	+0.263	.009	.002	2	1
HNSC	PRAC1 →	+0.380	+0.287	.002	.002	2	1
HNSC	OR6C75 →	+0.065	+0.303	.005	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

FAM189B vs CGB2 — HNSC

Explore this scatter interactively →