FAM189B

Across TCGA cell cohorts, FAM189B RNA expression is significantly associated with the RNA expression of many other genes, with 10,364 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAM189B-associated genes across cancer lineages are PYGO2, RUSC1, and SCAMP3. Each is linked with FAM189B in more than 16 cancer types. Because this analysis shows association rather than direction, both FAM189B-to-partner and partner-to-FAM189B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189B versus PYGO2 in BONE, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189B→partner) and Y-score (partner→FAM189B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PYGO2 →	+1.333	+1.412	<.001	<.001	3	17
BLOOD_Myeloma	RUSC1 →	+1.294	+1.270	.003	.002	2	17
SKIN	SCAMP3 →	+0.964	+0.769	<.001	<.001	3	16
BONE	USP21 →	+1.031	+0.838	<.001	<.001	3	16
OESOPHAGUS	NDUFS2 →	+0.871	+1.009	<.001	<.001	3	16
OVARY	UBQLN4 →	+1.080	+1.468	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,364 associations by consensus.

FAM189B vs PYGO2 — BONE

Explore this scatter interactively →