FAM189A2

Across TCGA cell cohorts, FAM189A2 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible FAM189A2-associated genes across cancer lineages are CRX, KRTAP13-2, and FOXI2. Each is linked with FAM189A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM189A2-to-partner and partner-to-FAM189A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRX grouped by FAM189A2-low versus FAM189A2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189A2→partner) and Y-score (partner→FAM189A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CRX →	+0.012	+4.392	<.001	.003	3	2
PANCREAS	KRTAP13-2 →	+0.035	+5.000	<.001	.006	3	1
PANCREAS	FOXI2 →	+0.049	+5.000	<.001	.006	3	1
PANCREAS	PRAMEF19 →	+0.013	+5.000	<.001	.006	3	1
PANCREAS	CCL18 →	+0.036	+5.000	<.001	.006	3	1
PANCREAS	SPRR5 →	+0.066	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

CRX by FAM189A2 expression — OESOPHAGUS

Explore this box plot interactively →