FAM187B

Across TCGA patient cohorts, FAM187B mutation is significantly associated with the RNA expression of many other genes, with 981 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM187B-associated genes across cancer lineages are SNORA48B, RNU6-649P, and MIR367. Each is linked with FAM187B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM187B-to-partner and partner-to-FAM187B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA48B grouped by FAM187B-low versus FAM187B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM187B→partner) and Y-score (partner→FAM187B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	SNORA48B →	+0.423	+5.093	<.001	.008	3	2
UCEC	RNU6-649P →	+0.245	+2.434	<.001	.009	3	2
LUSC	MIR367 →	+0.672	+5.151	<.001	.007	3	2
UCEC	NFKBIB →	+0.511	+3.732	<.001	<.001	3	2
UCEC	RRP9 →	+0.496	+3.512	.001	.002	3	2
UCEC	MBOAT7 →	+0.432	+2.343	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 981 associations by consensus.

SNORA48B by FAM187B expression — LUSC

Explore this box plot interactively →