FAM187B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM187B RNA expression is significantly associated with the go_rna of many other GO terms, with 326 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible FAM187B-associated GO terms across cancer lineages are Positive regulation of execution phase of apoptosis, Isoprenoid catabolic process, and Terpenoid catabolic process. Each is linked with FAM187B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM187B-to-partner and partner-to-FAM187B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of execution phase of apoptosis grouped by FAM187B-low versus FAM187B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM187B→partner) and Y-score (partner→FAM187B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHPositive regulation of execution phase of apoptosis →+0.079+0.017.002.00434
LUNG_NSCLC_LUADIsoprenoid catabolic process →-0.764-0.018.002.00134
LUNG_NSCLC_LUADTerpenoid catabolic process →-0.732-0.017.003.00334
LUNG_NSCLC_LUSCCellular response to UV-A →-0.244-0.016.004.00933
STOMACHRegulation of execution phase of apoptosis →+0.082+0.017.002.00424
LUNG_NSCLC_LUADNeurotrophin TRK receptor signaling pathway →-0.065-0.014.005<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 326 associations by consensus.

Positive regulation of execution phase of apoptosis by FAM187B expression — STOMACH

Box plot of Positive regulation of execution phase of apoptosis in FAM187B-low vs FAM187B-high samples in STOMACH.

Explore this box plot interactively →

Exploration