FAM184B

Across TCGA patient cohorts, FAM184B mutation is significantly associated with the RNA expression of many other genes, with 5,263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM184B-associated genes across cancer lineages are CCL5, CHASERR, and TMEM269. Each is linked with FAM184B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM184B-to-partner and partner-to-FAM184B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL5 grouped by FAM184B-low versus FAM184B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184B→partner) and Y-score (partner→FAM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL5 →	+0.815	+1.606	.001	<.001	3	2
UCEC	CHASERR →	+0.457	+3.119	<.001	<.001	3	2
COAD	TMEM269 →	+0.192	+2.663	.001	.005	3	2
UCEC	CCL4 →	+0.606	+1.420	.002	.002	3	2
UCEC	TUBGCP5 →	+0.431	+2.032	<.001	<.001	3	2
COAD	SRCIN1 →	-0.775	-3.700	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,263 associations by consensus.

CCL5 by FAM184B expression — UCEC

Explore this box plot interactively →