FAM184B

Across TCGA patient cohorts, FAM184B mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM184B-associated genes across cancer lineages are ATM, Lck, and MSH6. Each is linked with FAM184B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM184B-to-partner and partner-to-FAM184B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by FAM184B-low versus FAM184B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184B→partner) and Y-score (partner→FAM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.617	-2.321	<.001	<.001	3	3
COAD	Lck →	+0.298	+2.347	.030	.019	3	2
COAD	MSH6 →	-0.456	-2.296	.009	.035	3	2
UCEC	Caspase-7-cleavedD198 →	+0.557	+1.906	.003	.014	3	2
UCEC	4E-BP1 →	+0.317	+3.807	<.001	<.001	3	2
COAD	IGFBP2 →	+0.886	+3.000	.004	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

ATM by FAM184B expression — UCEC

Explore this box plot interactively →