FAM184B

Across TCGA cell cohorts, FAM184B mutation is significantly associated with the RNA expression of many other genes, with 714 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM184B-associated genes across cancer lineages are MSGN1, C9orf92, and KRTAP2-4. Each is linked with FAM184B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM184B-to-partner and partner-to-FAM184B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by FAM184B-low versus FAM184B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184B→partner) and Y-score (partner→FAM184B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.044	+2.345	.004	.007	3	2
PANCREAS	C9orf92 →	+0.197	+5.000	<.001	.006	3	1
SOFT_TISSUE	KRTAP2-4 →	+0.122	+4.930	<.001	.008	3	1
LUNG_NSCLC_LUAD	CSH1 →	+0.046	+4.343	<.001	.002	3	1
LUNG_NSCLC_LUAD	ASZ1 →	+0.667	+4.157	<.001	.003	3	1
LUNG_NSCLC_LUAD	KCNK18 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 714 associations by consensus.

MSGN1 by FAM184B expression — LARGE_INTESTINE

Explore this box plot interactively →