FAM181B

Across TCGA patient cohorts, FAM181B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,200 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM181B-associated proteins across cancer lineages are MAP1A, MAP6, and SHROOM2. Each is linked with FAM181B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM181B-to-partner and partner-to-FAM181B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM181B versus MAP1A in UCEC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM181B→partner) and Y-score (partner→FAM181B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP1A →	+0.440	+0.815	<.001	<.001	3	4
PDAC	MAP6 →	+0.596	+0.173	<.001	<.001	3	4
GBM	SHROOM2 →	+0.437	+1.162	<.001	<.001	3	4
COAD	TOP1 →	-0.466	-0.190	<.001	.002	3	4
GBM	ZBTB47_T390 →	+0.629	+1.379	<.001	<.001	3	4
GBM	EPN2 →	+0.369	+0.968	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,200 associations by consensus.

FAM181B vs MAP1A — UCEC

Explore this scatter interactively →