FAM181B

Across TCGA patient cohorts, FAM181B mutation is significantly associated with the RNA expression of many other genes, with 156 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM181B-associated genes across cancer lineages are RNU6-1013P, LINC02113, and IGHD5-5. Each is linked with FAM181B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM181B-to-partner and partner-to-FAM181B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1013P grouped by FAM181B-low versus FAM181B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM181B→partner) and Y-score (partner→FAM181B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1013P →	+0.146	+3.973	.008	.008	3	2
COAD	LINC02113 →	+0.655	+3.189	<.001	<.001	3	2
UCEC	IGHD5-5 →	+1.131	+8.066	<.001	.007	3	2
CESC	MIR627 →	+0.611	+5.010	<.001	.009	3	1
CESC	TRAJ30 →	+0.883	+5.103	<.001	.008	3	1
CESC	ARF4P3 →	+0.110	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 156 associations by consensus.

RNU6-1013P by FAM181B expression — COAD

Explore this box plot interactively →