FAM181B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM181B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,177 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM181B-associated GO terms across cancer lineages are Motile cilium assembly, Alternative mRNA splicing, via spliceosome, and Adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Each is linked with FAM181B in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM181B-to-partner and partner-to-FAM181B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Motile cilium assembly grouped by FAM181B-low versus FAM181B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM181B→partner) and Y-score (partner→FAM181B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYMotile cilium assembly →-0.034-0.451.002.00838
OVARYAlternative mRNA splicing, via spliceosome →+0.112+0.306<.001<.00137
OVARYAdenylate cyclase-modulating G protein-coupled receptor signaling pathway →-0.062-0.363<.001<.00137
OVARYAxoneme assembly →-0.047-0.302<.001<.00137
OVARYPotassium ion transport →-0.074-0.362<.001<.00137
OVARYPotassium ion transmembrane transport →-0.070-0.378<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,177 associations by consensus.

Motile cilium assembly by FAM181B expression — OVARY

Box plot of Motile cilium assembly in FAM181B-low vs FAM181B-high samples in OVARY.

Explore this box plot interactively →

Exploration