FAM181A

Across TCGA patient cohorts, FAM181A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,052 significant associations in total. LGG shows the largest number of these associations.

The most reproducible FAM181A-associated GO terms across cancer lineages are Embryonic heart tube development, Labyrinthine layer development, and Specification of symmetry. Each is linked with FAM181A in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM181A-to-partner and partner-to-FAM181A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic heart tube development grouped by FAM181A-low versus FAM181A-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM181A→partner) and Y-score (partner→FAM181A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Embryonic heart tube development →	+0.030	+0.523	<.001	<.001	3	13
THYM	Labyrinthine layer development →	+0.052	+0.340	<.001	<.001	3	12
TGCT	Specification of symmetry →	+0.038	+0.899	<.001	<.001	3	12
STAD	Proton motive force-driven ATP synthesis →	+0.090	+0.110	<.001	<.001	3	12
STAD	Neural tube formation →	+0.066	+0.075	<.001	<.001	3	12
STAD	Embryonic placenta development →	+0.064	+0.086	<.001	<.001	1	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,052 associations by consensus.

Embryonic heart tube development by FAM181A expression — TGCT

Explore this box plot interactively →