FAM181A

Across TCGA patient cohorts, FAM181A protein abundance is significantly associated with the protein abundance of many other proteins, with 934 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM181A-associated proteins across cancer lineages are PI4KA_S1424, ATG16L1_S269, and ACO1_T628. Each is linked with FAM181A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM181A-to-partner and partner-to-FAM181A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM181A versus PI4KA_S1424 in GBM, with a Pearson correlation of 0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM181A→partner) and Y-score (partner→FAM181A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PI4KA_S1424 →	+0.472	+0.475	.005	.007	2	1
GBM	ATG16L1_S269 →	+0.289	+0.406	.005	.001	1	1
GBM	ACO1_T628 →	+1.286	+0.626	<.001	.006	1	1
GBM	BLVRB →	+1.248	+0.442	.004	.001	1	1
GBM	BMP2K_S1029 →	+1.039	+0.453	.002	.007	1	1
GBM	BPGM →	+0.964	+0.439	.005	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

FAM181A vs PI4KA_S1424 — GBM

Explore this scatter interactively →