Across TCGA cell cohorts, FAM180A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM180A-associated genes across cancer lineages are CCL15 and MAGEB4. Each is linked with FAM180A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM180A-to-partner and partner-to-FAM180A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180A→partner) and Y-score (partner→FAM180A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCL15 →	+0.027	+4.095	.003	.009	3	1
LARGE_INTESTINE	MAGEB4 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

FAM180A survival (RNA) · tumor vs normal (RNA) · all FAM180A data types