FAM178B

Across TCGA patient cohorts, FAM178B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,351 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM178B-associated proteins across cancer lineages are SORBS3_S348, ARHGAP39_S366, and PDLIM2. Each is linked with FAM178B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM178B-to-partner and partner-to-FAM178B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM178B versus SORBS3_S348 in CCRCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM178B→partner) and Y-score (partner→FAM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SORBS3_S348 →	+0.988	+0.128	<.001	<.001	3	4
GBM	ARHGAP39_S366 →	+0.404	+0.414	<.001	<.001	2	4
CCRCC	PDLIM2 →	+0.330	+0.073	<.001	<.001	3	3
GBM	SEPTIN7 →	+0.264	+0.431	<.001	<.001	3	3
CCRCC	SEPTIN8 →	+0.370	+0.074	<.001	<.001	3	3
GBM	SH3BGRL →	+0.225	+0.386	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,351 associations by consensus.

FAM178B vs SORBS3_S348 — CCRCC

Explore this scatter interactively →