Across TCGA patient cohorts, FAM177B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM177B-associated genes across cancer lineages are FoxM1, Gab2, and eIF4G. Each is linked with FAM177B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM177B-to-partner and partner-to-FAM177B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM177B→partner) and Y-score (partner→FAM177B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.253	+3.009	.030	.019	3	2
UCEC	Gab2 →	+0.322	+2.000	.045	.032	3	2
UCEC	eIF4G →	+0.348	+3.459	.012	.005	3	1
UCEC	INPP4B →	-0.293	-3.169	.045	.018	3	1
UCEC	Paxillin →	+0.266	+3.179	.023	.010	3	1
UCEC	PCNA →	+0.268	+2.000	.005	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

FAM177B survival (RNA) · tumor vs normal (RNA) · all FAM177B data types