FAM172A

Across TCGA patient cohorts, FAM172A mutation is significantly associated with the RNA expression of many other genes, with 1,735 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM172A-associated genes across cancer lineages are KRTAP12-6P, MIR1302-5, and RN7SL539P. Each is linked with FAM172A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM172A-to-partner and partner-to-FAM172A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP12-6P grouped by FAM172A-low versus FAM172A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM172A→partner) and Y-score (partner→FAM172A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KRTAP12-6P →	+0.298	+5.212	.001	.007	3	2
BLCA	MIR1302-5 →	+0.235	+4.899	<.001	.005	3	2
BRCA	RN7SL539P →	+0.079	+8.471	<.001	.005	3	1
COAD	OR2G2 →	+0.098	+6.003	<.001	.002	3	1
UCEC	LINC01607 →	-0.698	-3.071	<.001	<.001	3	1
UCEC	POM121C →	+0.426	+2.931	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,735 associations by consensus.

KRTAP12-6P by FAM172A expression — COAD

Explore this box plot interactively →