FAM170B-AS1

Across TCGA pan-cancer cohorts, FAM170B-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated FAM170B-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher FAM170B-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM170B-AS1 expression acts as an unfavorable survival marker, although some lineages such as THCA and UCS show a favorable association.

LUSC, LAML, and THCA are the cancer types where FAM170B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	IV	0.001	0.673	.014	48	view →
LAML	DFS	Median	All	0.460	0.680	.001	48	view →
THCA	DFS	Quartile	II,III,IV	1.000	0.435	.002	23	view →
UCS	DFS	Tertile	All	0.485	0.175	.022	22	view →
ACC	DFS	Tertile	II,III,IV	0.485	0.693	.043	19	view →
OV	DFS	Tertile	III,IV	0.250	0.139	.029	18	view →
GBM	DFS	Tertile	All	0.135	0.270	.013	9	view →
READ	OS	Tertile	All	0.725	0.924	.047	9	view →
BRCA	DFS	Tertile	IV	0.378	0.653	.037	6	view →
KIRP	DFS	Tertile	All	0.766	0.881	.034	3	view →
LUAD	OS	Quartile	III,IV	0.746	0.621	.042	3	view →
STAD	OS	Median	II,III,IV	0.555	0.300	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

FAM170B-AS1–LUSC (OS)

Open the LUSC breakdown →