FAM170B-AS1

Across TCGA pan-cancer cohorts, FAM170B-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FAM170B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FAM170B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM170B-AS1 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

THCA, BRCA, and HNSC are the cancer types where FAM170B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM170B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	+0.463	<.001	7	view →
BRCA	All	All	−0.015	<.001	6	view →
HNSC	All	III,IV	+0.014	.021	4	view →
KIRC	Male	All	+0.011	.003	3	view →
KIRP	All	All	−0.011	.008	2	view →
KICH	Male	All	−0.011	.028	2	view →
LUSC	All	II,III,IV	−0.024	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FAM170B-AS1–THCA

Open the THCA breakdown →