Across TCGA cell cohorts, FAM169A mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM169A-associated genes across cancer lineages are OR2L3, RBMY1J, and C20orf173. Each is linked with FAM169A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM169A-to-partner and partner-to-FAM169A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM169A→partner) and Y-score (partner→FAM169A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2L3 →	+0.076	+4.523	<.001	.004	3	2
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	C20orf173 →	+0.054	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	S100A7A →	+0.026	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR2AK2 →	+0.043	+4.191	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR10AG1 →	+0.036	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

FAM169A survival (RNA) · tumor vs normal (RNA) · all FAM169A data types