FAM168B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM168B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,262 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM168B-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Heterochromatin organization, and Nuclear export. Each is linked with FAM168B in more than 16 cancer types. Because this analysis shows association rather than direction, both FAM168B-to-partner and partner-to-FAM168B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by FAM168B-low versus FAM168B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM168B→partner) and Y-score (partner→FAM168B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of mitotic cytokinesis →+0.142+0.818.002.003317
UPPER_AERODIGESTIVE_TRACTHeterochromatin organization →+0.069+1.071<.001<.001316
SOFT_TISSUENuclear export →+0.097+0.937<.001.001316
BONENegative regulation of gene expression, epigenetic →+0.092+0.783.002.003316
BONEEstablishment of spindle localization →+0.140+0.934<.001<.001316
STOMACHPositive regulation of T-helper 17 cell lineage commitment →+0.239+0.933.001.002315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,262 associations by consensus.

Positive regulation of mitotic cytokinesis by FAM168B expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of mitotic cytokinesis in FAM168B-low vs FAM168B-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration