FAM167B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM167B mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM167B-associated genes across cancer lineages are RNU6-670P, RNU6-879P, and RN7SL464P. Each is linked with FAM167B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM167B-to-partner and partner-to-FAM167B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM167B→partner) and Y-score (partner→FAM167B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-670P →+0.560+4.893.002.00532
COADRNU6-879P →+1.290+4.295<.001.00832
COADRN7SL464P →+0.586+4.602<.001.00832
COADHMGB1P23 →+0.469+4.237.002.00832
COADMIR548S →+1.276+5.730<.001<.00132
LGGRNU6ATAC9P →+0.470+6.491<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

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