FAM166C

Across TCGA patient cohorts, FAM166C protein abundance is significantly associated with the RNA expression of many other genes, with 325 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM166C-associated genes across cancer lineages are OVOL3, GLI1, and RNGTT. Each is linked with FAM166C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM166C-to-partner and partner-to-FAM166C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM166C versus OVOL3 in LUAD, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166C→partner) and Y-score (partner→FAM166C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OVOL3 →	-0.664	-0.586	<.001	.008	3	1
LUAD	GLI1 →	+0.497	+0.571	.006	.002	3	1
LUAD	RNGTT →	+0.412	+0.385	.002	.001	3	1
LUAD	RBM24 →	+0.291	+0.554	.002	.003	3	1
LUAD	SMAP1 →	+0.527	+0.454	.001	.001	3	1
LUAD	GMDS →	+0.877	+0.631	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 325 associations by consensus.

FAM166C vs OVOL3 — LUAD

Explore this scatter interactively →