Across TCGA cell cohorts, FAM166A mutation is significantly associated with the mutation status of many other genes, with 2,553 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM166A-associated genes across cancer lineages are TMEM63A, KIF7, and CNKSR1. Each is linked with FAM166A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM166A-to-partner and partner-to-FAM166A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM166A→partner) and Y-score (partner→FAM166A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TMEM63A →	+4.187	+5.000	.008	.008	1	4
BLOOD_Leukemia	KIF7 →	+2.285	+3.364	.006	.006	1	4
LARGE_INTESTINE	CNKSR1 →	+3.799	+3.329	.005	.005	1	4
LUNG_NSCLC_LUAD	ANO8 →	+5.772	+5.772	.002	.002	1	4
LUNG_NSCLC_LUAD	CLIP2 →	+4.187	+5.000	.008	.008	1	4
BLOOD_Leukemia	CREBBP →	+2.147	+4.152	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,553 associations by consensus.

Exploration

FAM166A survival (RNA) · tumor vs normal (RNA) · all FAM166A data types