FAM163A

Across TCGA patient cohorts, FAM163A mutation is significantly associated with the RNA expression of many other genes, with 542 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM163A-associated genes across cancer lineages are OOSP1P1, RNU6-6P, and LINC00551. Each is linked with FAM163A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM163A-to-partner and partner-to-FAM163A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP1P1 grouped by FAM163A-low versus FAM163A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM163A→partner) and Y-score (partner→FAM163A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OOSP1P1 →	+0.178	+4.680	<.001	<.001	3	2
UCEC	RNU6-6P →	+0.625	+2.227	<.001	.008	3	1
UCEC	LINC00551 →	+0.195	+3.109	<.001	.001	3	1
UCEC	ZNF280B →	+0.590	+3.470	.005	.003	3	1
UCEC	MIR6797 →	+0.839	+2.747	.006	.008	3	1
SKCM	ATXN3L →	+0.201	+3.669	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 542 associations by consensus.

OOSP1P1 by FAM163A expression — SKCM

Explore this box plot interactively →