FAM161A

Across TCGA patient cohorts, FAM161A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,866 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM161A-associated proteins across cancer lineages are MSH2, SMAD4, and RFC2. Each is linked with FAM161A in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM161A-to-partner and partner-to-FAM161A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM161A versus MSH2 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161A→partner) and Y-score (partner→FAM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH2 →	+0.649	+0.744	<.001	<.001	3	8
OV	SMAD4 →	+0.275	+0.760	.004	.003	3	7
HNSC	RFC2 →	+0.435	+0.865	<.001	<.001	3	7
GBM	SUPT16H →	+0.461	+0.441	.002	.007	3	7
LSCC	MCM2_S139 →	+0.749	+0.854	<.001	<.001	3	7
GBM	MCM5 →	+0.585	+0.378	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,866 associations by consensus.

FAM161A vs MSH2 — LSCC

Explore this scatter interactively →