FAM160B1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM160B1 mutation is significantly associated with the RNA expression of many other genes, with 1,431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160B1-associated genes across cancer lineages are OIP5, TXN, and C9orf78. Each is linked with FAM160B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM160B1-to-partner and partner-to-FAM160B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by FAM160B1-low versus FAM160B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160B1→partner) and Y-score (partner→FAM160B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOIP5 →+0.591+1.799.002.00133
UCECTXN →+0.355+2.039.009.00533
UCECC9orf78 →+0.272+2.534.004<.00133
UCECLLPH →+0.334+1.686.004.00633
UCECEAF2 →+0.419+2.080<.001<.00133
UCECGTF2E2 →+0.381+2.376.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,431 associations by consensus.

OIP5 by FAM160B1 expression — UCEC

Box plot of OIP5 in FAM160B1-low vs FAM160B1-high samples in UCEC.

Explore this box plot interactively →

Exploration