FAM157A

Across TCGA pan-cancer cohorts, FAM157A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM157A data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM157A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM157A expression acts as an unfavorable survival marker.

COAD are the cancer types where FAM157A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.028	0.668	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

FAM157A–COAD (DFS)

Open the COAD breakdown →