FAM157A

Across TCGA patient cohorts, FAM157A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,950 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM157A-associated proteins across cancer lineages are ATP13A3_S817, ARHGEF17_S1331, and YY1AP1_S724. Each is linked with FAM157A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM157A-to-partner and partner-to-FAM157A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM157A versus ATP13A3_S817 in UCEC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM157A→partner) and Y-score (partner→FAM157A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP13A3_S817 →	+0.342	+0.456	<.001	.003	3	4
PDAC	ARHGEF17_S1331 →	-0.533	-0.361	.001	<.001	3	3
LSCC	YY1AP1_S724 →	+0.482	+0.715	<.001	<.001	3	3
LSCC	NAB2_S171 →	+0.359	+0.561	<.001	<.001	3	3
HNSC	NT5C3A →	-0.483	-0.631	.006	.009	3	3
LSCC	ACAP2 →	+0.479	+0.731	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,950 associations by consensus.

FAM157A vs ATP13A3_S817 — UCEC

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