FAM153CP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM153CP mutation is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM153CP-associated genes across cancer lineages are FAM197Y5, CYP2C60P, and GTF2F2P2. Each is linked with FAM153CP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM153CP-to-partner and partner-to-FAM153CP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM153CP→partner) and Y-score (partner→FAM153CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADFAM197Y5 →+0.039+7.930<.001.00832
SKCMCYP2C60P →+0.597+4.884<.001.00432
SKCMGTF2F2P2 →+0.043+4.385<.001.00831
SKCMTSPY12P →+0.072+5.634<.001.00131
SKCMCASP3P1 →+0.050+4.495<.001.00731
SKCMRN7SL273P →+0.421+3.801<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

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