FAM153B

Across TCGA patient cohorts, FAM153B mutation is significantly associated with the RNA expression of many other genes, with 1,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM153B-associated genes across cancer lineages are MIR548D2, RHOXF2, and RPL22P22. Each is linked with FAM153B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM153B-to-partner and partner-to-FAM153B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR548D2 grouped by FAM153B-low versus FAM153B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM153B→partner) and Y-score (partner→FAM153B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR548D2 →	+0.388	+5.355	.008	.005	3	2
LUAD	RHOXF2 →	+0.916	+3.659	<.001	.009	3	2
SKCM	RPL22P22 →	+0.226	+4.072	<.001	.001	3	2
UCEC	RN7SL134P →	+0.201	+2.599	<.001	.009	3	2
LIHC	PER3P1 →	+0.078	+5.355	<.001	.005	3	1
LIHC	NBEAP5 →	+0.195	+5.758	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,170 associations by consensus.

MIR548D2 by FAM153B expression — LIHC

Explore this box plot interactively →