FAM153B

Across TCGA patient cohorts, FAM153B mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM153B-associated genes across cancer lineages are Epithelial cells, CD4+ Tem, and Tregs. Each is linked with FAM153B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM153B-to-partner and partner-to-FAM153B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by FAM153B-low versus FAM153B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM153B→partner) and Y-score (partner→FAM153B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.094	-2.321	.009	.036	3	2
LIHC	CD4+ Tem →	+0.046	+4.283	<.001	.023	3	1
LIHC	Tregs →	+0.069	+4.237	.004	.025	3	1
LIHC	CD4+ Tcm →	+0.012	+5.647	.011	.004	3	1
COAD	MPP →	+0.026	+2.818	.003	.023	3	1
COAD	Preadipocytes →	+0.030	+5.491	.022	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Epithelial cells by FAM153B expression — UCEC

Explore this box plot interactively →