FAM153A

Across TCGA pan-cancer cohorts, FAM153A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM153A data layer compared with 19 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher FAM153A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM153A expression acts as an unfavorable survival marker.

STAD, ESCA, and SKCM are the cancer types where FAM153A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.215	0.676	.011	24	view →
ESCA	OS	Median	II,III,IV	0.206	0.686	.004	12	view →
SKCM	DFS	Median	All	0.340	0.623	.011	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM153A–STAD (OS)

Open the STAD breakdown →