FAM153A

Across TCGA patient cohorts, FAM153A mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM153A-associated genes across cancer lineages are VN1R91P, RN7SL440P, and MIR598. Each is linked with FAM153A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM153A-to-partner and partner-to-FAM153A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R91P grouped by FAM153A-low versus FAM153A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM153A→partner) and Y-score (partner→FAM153A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VN1R91P →	+0.145	+4.917	<.001	.003	3	2
UCEC	RN7SL440P →	+0.173	+3.344	<.001	.008	3	2
SKCM	MIR598 →	+0.431	+2.915	<.001	.008	3	2
SKCM	TRBV22OR9-2 →	+0.109	+4.408	<.001	.005	3	1
SKCM	LINC01815 →	+0.049	+4.634	<.001	.003	3	1
SKCM	RN7SL502P →	+0.424	+3.054	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

VN1R91P by FAM153A expression — COAD

Explore this box plot interactively →