FAM151B

Across TCGA patient cohorts, FAM151B mutation is significantly associated with the RNA expression of many other genes, with 1,231 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM151B-associated genes across cancer lineages are RN7SL429P, CCDC172, and MIR4769. Each is linked with FAM151B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM151B-to-partner and partner-to-FAM151B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL429P grouped by FAM151B-low versus FAM151B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM151B→partner) and Y-score (partner→FAM151B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL429P →	+0.359	+5.404	<.001	.005	3	2
BLCA	CCDC172 →	+0.030	+5.411	.007	.005	3	2
UCEC	MIR4769 →	+0.381	+3.153	<.001	.006	3	2
UCEC	DUXAP3 →	+0.243	+2.525	<.001	.002	3	2
SKCM	SNORD115-48 →	+0.412	+7.816	<.001	.008	3	2
SKCM	RNU4-69P →	+0.248	+7.816	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,231 associations by consensus.

RN7SL429P by FAM151B expression — LUSC

Explore this box plot interactively →