FAM151B

Across TCGA pan-cancer cohorts, FAM151B RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of FAM151B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where FAM151B RNA is repressed in tumor relative to normal tissue. In most cancer types FAM151B is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, COAD, and LIHC are the cancer types where FAM151B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM151B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.085	<.001	10	view →
COAD	All	II,III,IV	+0.355	<.001	10	view →
LIHC	Male	All	+0.317	<.001	8	view →
BRCA	All	III,IV	+0.638	<.001	6	view →
THCA	Male	III,IV	−0.238	.001	6	view →
CHOL	All	All	+0.713	<.001	3	view →
PRAD	All	All	+0.288	<.001	2	view →
UCEC	All	All	+0.228	.038	2	view →
LUSC	All	All	−0.186	.001	2	view →
ESCA	All	II,III,IV	+0.160	.009	2	view →
KIRC	All	All	−0.134	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

FAM151B–KICH

Open the KICH breakdown →