FAM151B

Across TCGA patient cohorts, FAM151B mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM151B-associated genes across cancer lineages are GAPDH, Ku80, and NDRG1_pT346. Each is linked with FAM151B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM151B-to-partner and partner-to-FAM151B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by FAM151B-low versus FAM151B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM151B→partner) and Y-score (partner→FAM151B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.661	+2.321	.014	.035	3	1
UCEC	Ku80 →	+0.276	+3.472	.020	.002	3	1
UCEC	NDRG1_pT346 →	+0.893	+2.321	<.001	.035	3	1
UCEC	PKC-a_pS657 →	-0.417	-2.990	.029	.036	3	1
UCEC	Rad50 →	-0.302	-2.321	.013	.035	3	1
UCEC	S6_pS240_S244 →	+0.543	+2.820	.007	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

GAPDH by FAM151B expression — UCEC

Explore this box plot interactively →