FAM13C

Across TCGA cell cohorts, FAM13C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,060 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible FAM13C-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Nucleoside triphosphate metabolic process, and Transport along microtubule. Each is linked with FAM13C in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM13C-to-partner and partner-to-FAM13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven ATP synthesis grouped by FAM13C-low versus FAM13C-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM13C→partner) and Y-score (partner→FAM13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Proton motive force-driven ATP synthesis →	+0.051	+0.317	.001	.003	3	8
BONE	Nucleoside triphosphate metabolic process →	+0.101	+1.371	.001	.004	3	8
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.048	+0.757	.003	.009	3	8
SKIN	Aerobic electron transport chain →	+0.081	+0.661	<.001	<.001	3	7
LIVER	Regulation of intracellular transport →	+0.063	+1.961	.001	.001	3	7
SKIN	ATP synthesis coupled electron transport →	+0.084	+0.661	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,060 associations by consensus.

Proton motive force-driven ATP synthesis by FAM13C expression — BLOOD_Lymphoma

Explore this box plot interactively →