FAM13A

Across TCGA cell cohorts, FAM13A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,507 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM13A-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Lysosomal transport, and Protein targeting to vacuole. Each is linked with FAM13A in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM13A-to-partner and partner-to-FAM13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by FAM13A-low versus FAM13A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM13A→partner) and Y-score (partner→FAM13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mRNA metabolic process →	+0.072	+1.176	<.001	.006	3	9
LUNG_NSCLC_LUAD	Lysosomal transport →	+0.046	+0.938	.001	<.001	3	8
BLOOD_Lymphoma	Protein targeting to vacuole →	+0.056	+1.094	<.001	<.001	3	8
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.063	+0.950	.008	.004	3	7
URINARY_TRACT	Schwann cell development →	+0.125	+1.520	.001	.001	3	7
LUNG_SCLC	Vesicle budding from membrane →	+0.048	+1.142	.006	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,507 associations by consensus.

Positive regulation of mRNA metabolic process by FAM13A expression — SOFT_TISSUE

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