FAM138A

Across TCGA patient cohorts, FAM138A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,698 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM138A-associated GO terms across cancer lineages are Protein localization to chromosome, Regulation of cell fate commitment, and Purine ribonucleotide salvage. Each is linked with FAM138A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM138A-to-partner and partner-to-FAM138A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by FAM138A-low versus FAM138A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM138A→partner) and Y-score (partner→FAM138A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to chromosome →	+0.125	+0.008	<.001	.008	3	3
STAD	Regulation of cell fate commitment →	+0.083	+0.009	<.001	.003	3	2
LUSC	Purine ribonucleotide salvage →	+0.090	+0.005	<.001	.001	3	2
LAML	Negative regulation of cholesterol storage →	+0.099	+0.022	<.001	.007	3	2
STAD	Electron transport chain →	+0.152	+0.010	<.001	.001	3	2
STAD	Microtubule organizing center organization →	+0.109	+0.008	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,698 associations by consensus.

Protein localization to chromosome by FAM138A expression — STAD

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