FAM136A

Across TCGA patient cohorts, FAM136A RNA expression is significantly associated with the protein abundance of many other proteins, with 21,540 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM136A-associated proteins across cancer lineages are MCM3, XPO5, and DDX5. Each is linked with FAM136A in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM136A-to-partner and partner-to-FAM136A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM136A versus MCM3 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM136A→partner) and Y-score (partner→FAM136A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM3 →	+0.627	+0.484	<.001	<.001	3	9
LSCC	XPO5 →	+0.663	+0.679	<.001	<.001	3	8
BRCA	DDX5 →	+0.310	+0.505	<.001	<.001	3	8
HNSC	CAD →	+0.421	+0.791	<.001	<.001	3	8
LSCC	POLR2H →	+0.401	+0.494	<.001	<.001	3	8
LSCC	RFC4 →	+0.531	+0.730	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,540 associations by consensus.

FAM136A vs MCM3 — LSCC

Explore this scatter interactively →