FAM135B

Across TCGA patient cohorts, FAM135B protein abundance is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM135B-associated genes across cancer lineages are NDUFAF4P3, PSMD7, and SQLE. Each is linked with FAM135B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM135B-to-partner and partner-to-FAM135B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM135B versus NDUFAF4P3 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM135B→partner) and Y-score (partner→FAM135B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFAF4P3 →	+0.681	+0.435	.009	.005	3	2
BRCA	PSMD7 →	-0.496	-0.358	.003	.001	3	1
BRCA	SQLE →	-0.780	-0.311	.004	.007	3	1
BRCA	AICDA →	-0.091	-0.469	.004	.001	3	1
BRCA	PTBP3 →	-0.634	-0.457	.001	.001	3	1
BRCA	PAEP →	+0.738	+0.451	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

FAM135B vs NDUFAF4P3 — BRCA

Explore this scatter interactively →