FAM133CP

Across TCGA pan-cancer cohorts, FAM133CP RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FAM133CP data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher FAM133CP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM133CP expression acts as an unfavorable survival marker, although some lineages such as LUSC and THYM show a favorable association.

KICH, KIRC, and LUSC are the cancer types where FAM133CP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.744	0.972	.004	61	view →
KIRC	DFS	Tertile	All	0.544	0.801	.002	45	view →
LUSC	OS	Quartile	II,III,IV	0.730	0.499	.001	38	view →
UCEC	DFS	Quartile	IV	0.331	0.754	.003	34	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	31	view →
LUAD	DFS	Quartile	II,III,IV	0.487	0.773	.005	26	view →
THYM	OS	Median	All	0.973	0.756	.007	22	view →
LIHC	OS	Tertile	All	0.370	0.629	.004	15	view →
UCS	DFS	Tertile	III,IV	0.605	0.276	.030	14	view →
GBM	OS	Tertile	All	0.509	0.276	.015	12	view →
CESC	DFS	Quartile	IV	0.178	0.550	.005	12	view →
ESCA	DFS	Quartile	III,IV	0.555	0.268	.021	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FAM133CP–KICH (OS)

Open the KICH breakdown →