FAM133CP

Across TCGA pan-cancer cohorts, FAM133CP RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FAM133CP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM133CP RNA is repressed in tumor relative to normal tissue. In most cancer types FAM133CP is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and COAD are the cancer types where FAM133CP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM133CP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	−0.261	<.001	8	view →
KICH	Female	All	−0.209	.001	8	view →
COAD	All	III,IV	+0.212	.006	6	view →
THCA	All	All	−0.135	<.001	4	view →
HNSC	All	III,IV	+0.072	.033	4	view →
CHOL	Female	All	+0.649	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FAM133CP–KIRC

Open the KIRC breakdown →