FAM133B

Across TCGA patient cohorts, FAM133B protein abundance is significantly associated with the RNA expression of many other genes, with 5,584 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM133B-associated genes across cancer lineages are CEP192, RFC5, and TRIM45. Each is linked with FAM133B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM133B-to-partner and partner-to-FAM133B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM133B versus CEP192 in HNSC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM133B→partner) and Y-score (partner→FAM133B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEP192 →	+0.666	+0.376	<.001	<.001	3	4
LSCC	RFC5 →	+0.609	+0.331	.005	.004	3	4
HNSC	TRIM45 →	+0.787	+0.439	<.001	<.001	3	4
GBM	POLE →	+0.893	+0.856	<.001	.002	3	4
GBM	EZH2 →	+1.581	+0.966	.005	.004	3	3
PDAC	TMEM97 →	+1.218	+0.358	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,584 associations by consensus.

FAM133B vs CEP192 — HNSC

Explore this scatter interactively →