FAM133B

Across TCGA cell cohorts, FAM133B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,482 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM133B-associated GO terms across cancer lineages are Replication fork processing, DNA-templated DNA replication maintenance of fidelity, and Regulation of sister chromatid cohesion. Each is linked with FAM133B in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM133B-to-partner and partner-to-FAM133B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by FAM133B-low versus FAM133B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM133B→partner) and Y-score (partner→FAM133B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Replication fork processing →	+0.128	+0.636	.006	.003	2	16
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.107	+0.537	.004	.002	2	15
BLOOD_Myeloma	Regulation of sister chromatid cohesion →	+0.105	+1.061	.002	<.001	3	14
SOFT_TISSUE	Positive regulation of DNA recombination →	+0.083	+0.739	<.001	<.001	3	14
BREAST	Regulation of double-strand break repair →	+0.075	+0.635	<.001	.001	3	13
BONE	DNA integrity checkpoint signaling →	+0.095	+0.598	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,482 associations by consensus.

Replication fork processing by FAM133B expression — BONE

Explore this box plot interactively →