FAM133A

Across TCGA cell cohorts, FAM133A mutation is significantly associated with the drug of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM133A-associated genes across cancer lineages are AZD2014, PCI-34051, and ERK_2440. Each is linked with FAM133A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM133A-to-partner and partner-to-FAM133A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD2014 grouped by FAM133A-low versus FAM133A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM133A→partner) and Y-score (partner→FAM133A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD2014 →	+0.588	+2.649	.024	.046	3	1
LARGE_INTESTINE	PCI-34051 →	+0.401	+2.646	.037	.047	3	1
LARGE_INTESTINE	ERK_2440 →	+0.515	+2.649	.036	.046	3	1
LARGE_INTESTINE	630600 →	+0.748	+2.649	.015	.046	3	1
LARGE_INTESTINE	THR-102 →	+0.312	+2.722	.035	.040	3	1
LARGE_INTESTINE	VE-822 →	+0.661	+2.646	.020	.047	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

AZD2014 by FAM133A expression — LARGE_INTESTINE

Explore this box plot interactively →