FAM131B

Across TCGA patient cohorts, FAM131B mutation is significantly associated with the RNA expression of many other genes, with 1,906 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM131B-associated genes across cancer lineages are SKA3, MRPL11, and LIPE-AS1. Each is linked with FAM131B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM131B-to-partner and partner-to-FAM131B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA3 grouped by FAM131B-low versus FAM131B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131B→partner) and Y-score (partner→FAM131B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA3 →	+0.574	+2.413	.002	<.001	3	3
UCEC	MRPL11 →	+0.408	+1.684	.009	.007	3	3
SKCM	LIPE-AS1 →	+0.326	+2.328	<.001	.003	3	3
LIHC	SLC25A51P3 →	+0.068	+5.940	<.001	<.001	3	2
LIHC	OR13C3 →	+0.053	+4.544	<.001	.009	3	2
LIHC	MTND1P10 →	+0.112	+4.378	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,906 associations by consensus.

SKA3 by FAM131B expression — UCEC

Explore this box plot interactively →