FAM131A

Across TCGA patient cohorts, FAM131A protein abundance is significantly associated with the RNA expression of many other genes, with 326 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM131A-associated genes across cancer lineages are MCM5, KHNYN, and TM9SF1. Each is linked with FAM131A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131A-to-partner and partner-to-FAM131A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM131A versus MCM5 in GBM, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131A→partner) and Y-score (partner→FAM131A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM5 →	-0.746	-0.356	<.001	.003	3	1
GBM	KHNYN →	-0.599	-0.360	.004	.005	3	1
GBM	TM9SF1 →	-0.467	-0.517	.001	<.001	3	1
GBM	MAZ →	-0.556	-0.380	.007	.001	3	1
GBM	PPP1R37 →	-0.374	-0.277	.003	.007	3	1
GBM	PSMD3 →	-0.515	-0.376	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 326 associations by consensus.

FAM131A vs MCM5 — GBM

Explore this scatter interactively →