FAM131A

Across TCGA patient cohorts, FAM131A mutation is significantly associated with the RNA expression of many other genes, with 3,444 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM131A-associated genes across cancer lineages are RNA5SP419, RNA5SP422, and RN7SL248P. Each is linked with FAM131A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM131A-to-partner and partner-to-FAM131A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by FAM131A-low versus FAM131A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131A→partner) and Y-score (partner→FAM131A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.623	+1.961	<.001	.009	3	3
UCEC	RNA5SP422 →	+0.757	+1.893	<.001	.008	3	3
UCEC	RN7SL248P →	+0.066	+3.307	<.001	.003	3	2
UCEC	RN7SL478P →	+0.313	+2.506	<.001	<.001	3	2
UCEC	RNA5SP416 →	+0.595	+2.108	<.001	.006	3	2
HNSC	MIR5692A2 →	+0.352	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,444 associations by consensus.

RNA5SP419 by FAM131A expression — UCEC

Explore this box plot interactively →